Antibodies - Immunoglobulim

Test your understanding of the specific concepts, facts, and details covered in this TEXT document about antibody structure and function

Science mixed 8 Questions
Progress 0 / 8
Q1 Beginner 1 pts

According to the document, what are the two main chains that make up the basic structure of an IgG antibody? Video Reference:
"The molecule is made up of two heavy chains and two light chains...."

Select all correct answers
Q2 Intermediate 2 pts

The document mentions that the IgG molecule has a pseudo-axis of rotational symmetry. What does this mean? Video Reference:
"Also, you've got the rotational symmetry within this molecule, that the two halves of the molecule; ..."

Q3 Beginner 1 pts

According to the document, what does the term 'Fab' stand for in reference to antibody fragments? Video Reference:
"Fragment antigen binding, that's where the term Fab comes from...."

Q4 Advanced 3 pts

The document describes several antibody fragments that can be obtained through proteolysis or genetic engineering. Which of the following is NOT one of the fragments mentioned? Video Reference:
"To sum up, we've got the Fc fragment and the 'c' in this stands for the crystallizable fragment. We'..."

Q5 Intermediate 2 pts

According to the document, the variable domains of antibodies contain sub-regions referred to as framework regions and complementarity-determining regions. Video Reference:
"These are referred to as framework region 1, complementarity-determining region 1, framework region ..."

Q6 Advanced 3 pts

The document mentions that antibodies have glycosylation sites. Where is a commonly conserved glycosylation site located in IgG molecules? Video Reference:
"Then finally, an indicator on this diagram we've got a glycosylation site, which is commonly conserv..."

Q7 Beginner 1 pts

Based on the information provided in the document, antibodies have two antigen binding sites. Video Reference:
"What you can see is that the molecule has effectively a certain symmetry about it. It's actually a p..."

Q8 Intermediate 2 pts

According to the document, what specific immunological challenge do antibodies help address? Video Reference:
"Immunology presents us with a real problem, and that is that we don't know in advance what infectiou..."

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