Quiz about Thyroid Hormone Synthesis and Effects

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Q1 Beginner 1 pts

According to the document, what transporter concentrates iodide (I⁻) in the thyroid by 30-250x compared to blood? Video Reference:
"Transportador NIS (Na⁺/I⁻ symporter), acoplado a Na⁺/K⁺-ATPasa → concentra I⁻ 30–250× frente a sangr..."

NIS (Na⁺/I⁻ symporter) Pendrin MCT8 OATP1C1

Q2 Intermediate 1 pts

The document mentions that thyroglobulin (TG) has approximately how many tyrosine residues? Video Reference:
"RER + Golgi producen tiroglobulina (≈ 660 kDa) con ~70 residuos de tirosina..."

20 70 120 200

Q3 Beginner 1 pts

True or false: The thyroid gland stores hormone extracellularly in the colloid for weeks to months. Video Reference:
"La tiroides es la única glándula que almacena hormona en el exterior de la célula (en coloide) por s..."

True

False

Q4 Advanced 1 pts

Which deiodinase enzyme converts T4 to T3 in the central nervous system, pituitary, muscle and brown adipose tissue? Video Reference:
"D2 (SNC, hipóﬁsis, músculo, BAT): T4 → T3 in situ (clave para feedback y efectos locales)...."

D1 D2 D3 D4

Q5 Advanced 1 pts

True or false: Thyroid hormone receptors (TR) recruit corepressors in the absence of T3 ligand, leading to repressed basal transcription. Video Reference:
"Sin ligando (estado basal): TR recluta correpresores (NCoR/SMRT) + HDAC → cromatina cerrada → repres..."

True

False

Q6 Intermediate 1 pts

According to the document, what are two typical effects of hyperthyroidism on the liver? Video Reference:
"Hipertiroidismo: ↓ colesterol y TG plasmáticos, ↑ AGL..."

Decreased LDL receptor expression and increased cholesterol Decreased gluconeogenesis and glycogenolysis Decreased plasma cholesterol and increased fatty acids Increased triglycerides and steatosis

Q7 Advanced 1 pts

Which part of the brain is TRH synthesized in before reaching the pituitary via portal vessels? Video Reference:
"TRH (hipotálamo, PVN) → vasos porta → tirotropos (adenohipóﬁsis)..."

Arcuate nucleus Suprachiasmatic nucleus Paraventricular nucleus (PVN) Supraoptic nucleus

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Quiz about Thyroid Hormone Synthesis and Effects

According to the document, what transporter concentrates iodide (I⁻) in the thyroid by 30-250x compared to blood? Video Reference: "Transportador NIS (Na⁺/I⁻ symporter), acoplado a Na⁺/K⁺-ATPasa → concentra I⁻ 30–250× frente a sangr..."

The document mentions that thyroglobulin (TG) has approximately how many tyrosine residues? Video Reference: "RER + Golgi producen tiroglobulina (≈ 660 kDa) con ~70 residuos de tirosina..."

True or false: The thyroid gland stores hormone extracellularly in the colloid for weeks to months. Video Reference: "La tiroides es la única glándula que almacena hormona en el exterior de la célula (en coloide) por s..."

Which deiodinase enzyme converts T4 to T3 in the central nervous system, pituitary, muscle and brown adipose tissue? Video Reference: "D2 (SNC, hipóﬁsis, músculo, BAT): T4 → T3 in situ (clave para feedback y efectos locales)...."

True or false: Thyroid hormone receptors (TR) recruit corepressors in the absence of T3 ligand, leading to repressed basal transcription. Video Reference: "Sin ligando (estado basal): TR recluta correpresores (NCoR/SMRT) + HDAC → cromatina cerrada → repres..."

According to the document, what are two typical effects of hyperthyroidism on the liver? Video Reference: "Hipertiroidismo: ↓ colesterol y TG plasmáticos, ↑ AGL..."

Which part of the brain is TRH synthesized in before reaching the pituitary via portal vessels? Video Reference: "TRH (hipotálamo, PVN) → vasos porta → tirotropos (adenohipóﬁsis)..."